Publication Type
Publication Type
Peer Reviewed Journal
Mandatory Citation Fields
Authors
Hollinger, M,Abraha, F,Oscarson, S;
Year
2011
Month
January
Journal
Carbohydrate Research
Title
Synthesis of mucin O-glycan core structures as their p-nitro- and p-aminophenyl glycosides
Status
Published
Times Cited
Optional Fields
Search Keyword
Please enter separate search keywords on separate lines
Mucin O-glycan core structures Oxazolidinone protected glycosyl donors Oligosaccharide synthesis GLYCOSYLATION GLUCOSAMINE CARBOHYDRATE ANALOGS GLCNAC DONORS ACID
Volume
346
Issue
Start Page
1454
End Page
1466
Abstract
For the investigation of glycosidases, and for the construction of glycan arrays the p-nitrophenyl- and p-aminophenyl glycosides of mucin O-glycan core structures 1-7 and the 2,6-ST-antigen have been chemically synthesized using D-galactose as a precursor for GalNAc residues. GlcNAc residues have partly been introduced using a 4,6-di-O-benzoyl-2,3-N,O-oxazolidinone-protected donor, which allowed deprotection of the formed di- and tri-saccharides in one step using sodium methoxide. (C) 2011 Elsevier Ltd. All rights reserved.
Publisher Location
ISBN / ISSN
Edition
URL
DOI Link
DOI 10.1016/j.carres.2011.03.036
Grant Details
Grant Details